Sunday, January 13, 2013

What disorders affect the penis?

Some disorders that affect the penis include priapism, Peyronie's disease , balanitis, phimosis, paraphimosis, and penile cancer.


What is priapism? Priapism is a persistent, often painful erection lasting more than 4 hours in duration. The priapism erection is not associated with sexual activity and is not relieved by orgasm. It occurs when blood flows into the penis but is not adequately drained.

What causes priapism? Common causes of priapism include: 

  • Alcohol or drug abuse (especially cocaine)
  • Certain medications, including some antidepressants and blood pressure medications
  • Spinal cord problems
  • Injury to the genitals
  • Anesthesia
  • Penile injection therapy (a treatment for erectile dysfunction)
  • Blood diseases, including leukemia and sickle cell anemia.   

What is Peyronie's disease? Peyronie's disease is a condition in which a plaque, or hard lump, forms on the penis. The plaque may develop on the upper (more common) or lower side of the penis, in the layers that contain erectile tissue. The plaque often begins as a localized area of irritation and swelling (inflammation), and can develop into a hardened scar. The scarring reduces the elasticity of the penis in the area affected.

Peyronie's disease can occur in a mild form that heals without treatment in 6 -18 months. In these cases, the problem does not progress past the inflammation phase. In severe cases, the disease can be permanent. The hardened plaque reduces flexibility, causing pain and forcing the penis to bend or arc during erection.

In addition to the bending of the penis, Peyronie's disease can cause general pain as well as painful erections. It also can cause emotional distress, and affect a man's desire and ability to function during sex.

What causes Peyronie's disease?

The exact cause of Peyronie's disease is unknown. In people whose disease develops quickly, lasts a short time, and goes away without treatment, the likely cause is trauma (hitting or bending) that causes bleeding inside the penis. However, in some people, Peyronie's disease develops slowly and is severe enough to require surgical treatment. Other possible causes of Peyronie's disease include:

  • Vasculitis: This is an inflammation of blood or lymphatic vessels. This inflammation can lead to the formation of scar tissue.
  • Connective tissue disorders: According to the National Institutes of Health, about 30% of men with Peyronie's disease also develop disorders that affect the connective tissue in other parts of their bodies, such as the hands and feet. These conditions generally cause a thickening or hardening of the connective tissue. Connective tissue is specialized tissue -- such as cartilage, bone, and skin -- that acts to support other body tissues.
  • Heredity: Some studies suggest that a man who has a relative with Peyronie's disease is at greater risk for developing the disease himself.

What is balanitis? Balanitis is an inflammation of the head of the penis. A similar condition, balanoposthitis, refers to inflammation of the head of the penis and the foreskin. Symptoms of balanitis include redness or swelling, itching, rash, pain and a foul-smelling discharge.

What causes balanitis?

Balanitis most often occurs in men and boys who have not been circumcised (had their foreskin surgically removed), and who have poor hygiene. Inflammation can occur if the sensitive skin under the foreskin is not washed regularly, allowing sweat, debris, dead skin and bacteria to collect under the foreskin and cause irritation. The presence of tight foreskin may make it difficult to keep this area clean and can lead to irritation by a foul-smelling substance (smegma) that can accumulate under the foreskin.
Other causes of balanitis may include:
  • Dermatitis/Allergy: Dermatitis is an inflammation of the skin, often caused by an irritating substance or a contact allergy. Sensitivity to chemicals in certain products -- such as soaps, detergents, perfumes and spermicides -- can cause an allergic reaction, including irritation, itching, and a rash.
  • Infection: Infection with the yeast candida albicans (thrush) can result in an itchy, spotty rash. Certain sexually transmitted diseases -- including gonorrhea, herpes and syphilis -- can produce symptoms of balanitis.
In addition, men with diabetes are at greater risk for balanitis. Glucose (sugar) in the urine that is trapped under the foreskin serves as a breeding ground for bacteria.

What is phimosis? Phimosis is a condition in which the foreskin of the penis is so tight that it cannot be pulled back (retracted) to reveal the head of the penis.

What causes phimosis? Phimosis, which is seen most often in children, may be present at birth. It also can be caused by an infection, or by scar tissue that formed as a result of injury or chronic inflammation. Another cause of phimosis is balanitis, which leads to scarring and tightness of the foreskin. Immediate medical attention is necessary if the condition makes urination difficult or impossible.

What is paraphimosis? Paraphimosis occurs when the foreskin, once retracted, cannot return to its original location. It is a medical emergency that can cause serious complications if not treated.

What causes paraphimosis? Paraphimosis may occur after an erection or sexual activity, or as the result of injury to the head of the penis. With paraphimosis, the foreskin becomes stuck behind the ridge of the head of the penis. If this condition is prolonged, it can cause pain and swelling, and impair blood flow to the penis. In extreme cases, the lack of blood flow can result in the death of tissue (gangrene), and amputation of the penis may be necessary.

What is penile cancer? Penile cancer is a rare form of cancer that occurs when abnormal cells in the penis divide and grow uncontrolled. Certain benign (non-cancerous) tumors may progress and become cancer.

What causes penile cancer? The exact cause of penile cancer is not known, but there are certain risk factors for the disease. A risk factor is anything that increases a person's chance of getting a disease. The risk factors for cancer of the penis may include the following:

  • Uncircumcision: Men who are not circumcised at birth have a higher risk for getting cancer of the penis.
  • Human papilloma virus (HPV) infection: HPV includes more than 100 types of viruses that can cause warts (papillomas). Certain types of HPV can infect the reproductive organs and the anal area. These types of HPV are passed from one person to another during sexual contact.
  • Smoking: Smoking exposes the body to many cancer-causing chemicals that affect more than the lungs.
  • Smegma: Oily secretions from the skin can accumulate under the foreskin of the penis. The result is a thick, bad-smelling substance called smegma. If the penis is not cleaned thoroughly, the presence of smegma can cause irritation and inflammation.
  • Phimosis: This is a condition in which the foreskin becomes constricted and difficult to retract.
  • Treatment for psoriasis: The skin disease psoriasis is sometimes treated with a combination of medication and exposure to ultraviolet light, which may increase a person's risk for penile cancer.
  • Age: Over half of penile cancer occur in men over age 68.

What are the symptoms of penile cancer? Symptoms of penile cancer include growths or sores on the penis, abnormal discharge from the penis, and bleeding.


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